Endocrine Abstracts

Keywords: short stature, Noonan syndrome, Prader-Willi syndrome, Silver-Russell syndrome, genetic syndromesIntroduction: Short stature is one of the major components of dysmorphic syndromes. Growth failure may be due to a wide variety of mechanisms, either related to the growth hormone (GH)/insulin-like growth factor axis or to underlying unknown pathologies. At present, GH therapy is used in most syndromic disorders, although long-term studies evaluatin...

Introduction: Craniopharyngioma is a rare benign epithelial tumour arising from the pituitary stalk or pituitary gland, developing in the sellar and suprasellar region, it affects both adults and children, The clinical presentation may include endocrine symptoms suggestive of hypopituitarism, ophthalmologic symptoms, signs of intracranial hypertension and focal neurological signs. However, after surgical treatment, hypothalamic-pituitary endocrine damage is common. The aim of ...